diff --git a/src/rpc/blockchain.cpp b/src/rpc/blockchain.cpp
index f8d7d94abf..438b6ce6e6 100644
--- a/src/rpc/blockchain.cpp
+++ b/src/rpc/blockchain.cpp
@@ -1168,6 +1168,10 @@ static RPCHelpMan gettxoutsetinfo()
             throw JSONRPCError(RPC_INVALID_PARAMETER, "Querying specific block heights requires coinstatsindex");
         }
 
+        if (stats.m_hash_type == CoinStatsHashType::HASH_SERIALIZED) {
+            throw JSONRPCError(RPC_INVALID_PARAMETER, "hash_serialized_2 hash type cannot be queried for a specific block");
+        }
+
         pindex = ParseHashOrHeight(request.params[1], chainman);
     }
 
diff --git a/test/functional/feature_coinstatsindex.py b/test/functional/feature_coinstatsindex.py
index cef60c5731..d3adde5cc5 100755
--- a/test/functional/feature_coinstatsindex.py
+++ b/test/functional/feature_coinstatsindex.py
@@ -52,6 +52,7 @@ class CoinStatsIndexTest(BitcoinTestFramework):
         self._test_coin_stats_index()
         self._test_use_index_option()
         self._test_reorg_index()
+        self._test_index_rejects_hash_serialized()
 
     def block_sanity_check(self, block_info):
         block_subsidy = 50
@@ -298,6 +299,15 @@ class CoinStatsIndexTest(BitcoinTestFramework):
         self.wait_until(lambda: not try_rpc(-32603, "Unable to read UTXO set", node.gettxoutsetinfo, 'muhash'))
         assert_raises_rpc_error(-32603, "Unable to read UTXO set", node.gettxoutsetinfo, 'muhash', reorg_block)
 
+    def _test_index_rejects_hash_serialized(self):
+        self.log.info("Test that the rpc raises if the legacy hash is passed with the index")
+
+        msg = "hash_serialized_2 hash type cannot be queried for a specific block"
+        assert_raises_rpc_error(-8, msg, self.nodes[1].gettxoutsetinfo, hash_type='hash_serialized_2', hash_or_height=111)
+
+        for use_index in {True, False, None}:
+            assert_raises_rpc_error(-8, msg, self.nodes[1].gettxoutsetinfo, hash_type='hash_serialized_2', hash_or_height=111, use_index=use_index)
+
 
 if __name__ == '__main__':
     CoinStatsIndexTest().main()