diff --git a/test/functional/test_framework/test_framework.py b/test/functional/test_framework/test_framework.py
index 03cd127a7da..6c18ef47ab5 100755
--- a/test/functional/test_framework/test_framework.py
+++ b/test/functional/test_framework/test_framework.py
@@ -280,6 +280,8 @@ class BitcoinTestFramework(metaclass=BitcoinTestMetaClass):
             rpc_logger.removeHandler(h)
         if cleanup_tree_on_exit:
             shutil.rmtree(self.options.tmpdir)
+
+        self.nodes.clear()
         return exit_code
 
     # Methods to override in subclass test scripts.